prof. dr. S.W.C. van Mil
prof. dr. S.W.C. van Mil
- Center for Molecular Medicine
Research Programs
Biography
Biography
Saskia van Mil (PhD) is Professor of Molecular and Translational Metabolism at the University Medical Center Utrecht, and Director of the Center for Molecular Medicine (www.cmmutrecht.eu). She is a member of the governing board and scientific committee of the European Association for the Study of the Liver (www.easl.eu).
She received her PhD from the University of Utrecht in 2004, on the topic of genetic disorders of pediatric cholestasis. As a post-doc at Imperial College London, United Kingdom, she studied the role of the bile salt sensor farnesoid X receptor (FXR) in intrahepatic cholestasis of pregnancy.
Since then, she has been intrigued by the versatility in molecular mechanisms of transcription by the nuclear receptor FXR and its therapeutic potential. Having received funding from the Netherlands’ Organisation of Scientific Research (Veni, Vidi, Vici), European Commission, Dutch Digestive Disease Foundation and DSM, her group studies the molecular and translational aspects of energy metabolism in the liver and the intestine. Amongst other projects, her group studies the molecular mechanisms of FXR function in metabolic disorders (e.g. NASH) and disorders of intestinal integrity (e.g. IBD). For more information on her research, please visit www.vanmil-lab.org.
Side Activities
2020-2023 Governing Board and Scientific Committee member of the European Association for the Study of the Liver
Research Output (50)
Mózes Ferenc E., Lee Jenny A., Vali Yasaman, Alzoubi Osama, Staufer Katharina, Trauner Michael, Paternostro Rafael, Stauber Rudolf E., Holleboom Adriaan G., van Dijk Anne Marieke, Mak Anne Linde, Boursier Jérôme, de Saint Loup Marc, Shima Toshihide, Bugianesi Elisabetta, Gaia Silvia, Armandi Angelo, Shalimar , Lupșor-Platon Monica, Wong Vincent Wai Sun, Li Guanlin, Wong Grace Lai Hung, Cobbold Jeremy, Karlas Thomas, Wiegand Johannes, Sebastiani Giada, Tsochatzis Emmanuel, Liguori Antonio, Yoneda Masato, Nakajima Atsushi, Hagström Hannes, Akbari Camilla, Hirooka Masashi, Chan Wah Kheong, Mahadeva Sanjiv, Rajaram Ruveena, Zheng Ming Hua, George Jacob, Eslam Mohammed, Petta Salvatore, Pennisi Grazia, Viganò Mauro, Ridolfo Sofia, Aithal Guruprasad Padur, Palaniyappan Naaventhan, Lee Dae Ho, Ekstedt Mattias, Nasr Patrik, Cassinotto Christophe, van Mil Saskia, Aug 2023, In: The Lancet Gastroenterology and Hepatology. 8 , p. 704-713 10 p.
Wolthuis Joanna C., Magnúsdóttir Stefanía, Stigter Edwin, Tang Yuen Fung, Jans Judith, Gilbert Myrthe, van der Hee Bart, Langhout Pim, Gerrits Walter, Kies Arie, de Ridder Jeroen, van Mil Saskia 2 Feb 2023, In: Metabolomics. 19
de Wit Koos, Beuers Ulrich, Mukha Anna, Stigter Edwin, Gulersonmez M Can, Ramos Pittol Jose M, Middendorp Sabine, Takkenberg R Bart, van Mil Saskia W C 4 Dec 2022, In: Liver International. 43 , p. 649-659 11 p.
Madsen Maria Stahl, Broekema Marjoleine F., Madsen Martin Rønn, Koppen Arjen, Borgman Anouska, Gräwe Cathrin, Thomsen Elisabeth G.K., Westland Denise, Kranendonk Mariette E.G., Koerkamp Marian Groot, Hamers Nicole, Bonvin Alexandre M.J.J., Pittol José M.Ramos, Natarajan Kedar Nath, Kersten Sander, Holstege Frank C.P., Monajemi Houshang, van Mil Saskia W.C., Vermeulen Michiel, Kragelund Birthe B., Cassiman David, Mandrup Susanne, Kalkhoven Eric Dec 2022, In: Nature Communications. 13
Appelman Monique D, Hollaar Elle E, Schuijers Jurian, van Mil Saskia W C 2022, p. 243-253 11 p.
de Jong Judith C.W., Ijssennagger Noortje, van Mil Saskia W.C. 1 Nov 2021, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1867 , p. 1-9
Mukha Anna, Kalkhoven Eric, van Mil Saskia W.C. 1 Oct 2021, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1867 , p. 1-13 13 p.
Ijssennagger Noortje, van Rooijen Kristel S, Magnúsdóttir Stefanía, Ramos Pittol José M, Willemsen Ellen C L, de Zoete Marcel R, Baars Matthijs J D, Stege Paul B, Colliva Carolina, Pellicciari Roberto, Youssef Sameh A, de Bruin Alain, Vercoulen Yvonne, Kuipers Folkert, van Mil Saskia W C Oct 2021, In: JHEP reports : innovation in hepatology. 3 , p. 1-10
Appelman Monique D, van der Veen Suzanne W, van Mil Saskia W C 27 Sep 2021, In: Frontiers in Endocrinology. 12 , p. 1-13
Selvaraj Emmanuel Anandraj, Mózes Ferenc Emil, Jayaswal Arjun Narayan Ajmer, Zafarmand Mohammad Hadi, Vali Yasaman, Lee Jenny A., Levick Christina Kim, Young Liam Arnold Joseph, Palaniyappan Naaventhan, Liu Chang Hai, Aithal Guruprasad Padur, Romero-Gómez Manuel, Brosnan M. Julia, Tuthill Theresa A., Anstee Quentin M., Neubauer Stefan, Harrison Stephen A., Bossuyt Patrick M., Pavlides Michael, Anstee Quentin, Daly Ann, Johnson Katherine, Govaere Olivier, Cockell Simon, Tiniakos Dina, Bedossa Pierre, Oakley Fiona, Cordell Heather, Day Chris, Wonders Kristy, Bossuyt Patrick, Zafarmand Hadi, Lee Jenny, Ratziu Vlad, Clement Karine, Pais Raluca, Schuppan Detlef, Schattenberg Jörn, Vidal-Puig Toni, Vacca Michele, Rodrigues-Cuenca Sergio, Allison Mike, Kamzolas Ioannis, Petsalaki Evangelia, Oresic Matej, Hyötyläinen Tuulia, McGlinchey Aiden, Mato Jose M., Millet Oscar, van Mil Saskia, 2021, In: Journal of Hepatology. 75 , p. 770-785 16 p.