dr. N. (Neeltje) Steeghs
dr. N. (Neeltje) Steeghs
- Dept of Medical Oncology
Biography
Biography
Neeltje Steeghs, M.D., Ph.D. is a licensed Medical Oncologist and Clinical Pharmacologist. She served as chair of the Dutch Pharmacology Oncology Group and chair of the Dutch GIST consortium. Her main scientific interests are new drug development, including the performance of clinical phase I and early phase II trials, and the inclusion of pharmacokinetics and pharmacodynamics in these studies. She also has a major interest in the design aspects of early clinical studies.
Besides her clinical activities, she has been Clinical Assessor for the Medicines Evaluation Board of the European Medicines Agency (2009-2011), chair of the Dutch Sarcoma Study Group, board member for the Paediatric Oncology Research Foundation (2010-2013), Young investigator for the EORTC Soft Tissue and Bone Sarcoma Group (2013-2016), chair of the multidisciplinary expert board for the Center for Personalized Cancer Treatment (2012-2015) and Vice-Chair of the Medical Ethical Committee of the Netherlands Cancer Institute. She has also been board member for the Dutch Oncological Medicine Evaluation Board, the National Working Party for Cancer Drugs Interactions and the Translational Research Board of the Netherlands Cancer Institute. She has a.o. been editor of Gastrointestinal Stromal Tumor (GIST), and Pharmacology of Anti-Cancer Drugs.
She currently serves as Director for the National Platform of Early Phase Clinical Trials at Oncode Accelerator/University Medical Center Utrecht, as Director of the Early Drug Development Center and Clinical Research at the Netherlands Cancer Institute, in Amsterdam, the Netherlands and as advisor for several pharmaceutical companies.
Neeltje Steeghs has been principle investigator for many investigator initiated and industry sponsored clinical trials. She is regarded as a leading authority on mechanisms for safe and effective dosing of anticancer agents. She has authored or co-authored over 200 scientific papers, and has given numerous lectures on a variety of topics at international meetings.
Neeltje Steeghs was invited to join the ESMO 2024 Scientific Committee as member of the Developmental therapeutics track.
Research Output (75)
Giraud E. L., Westerdijk K., van der Kleij M. B.A., Guchelaar N. A.D., Meertens M., Bleckman R. F., Rieborn A., Mohammadi M., Roets E., Mathijssen R. H.J., Huitema A. D.R., Koolen S. L.W., Gelderblom H., Moes D. J.A.R., Reyners A. K.L., Touw D. J., Keizer-Heldens P., Oosten A. W., van der Graaf W. T.A., Steeghs N., van Erp N. P., Desar I. M.E., Jun 2024, In: ESMO open. 9
Lin Lishi, Barkman Hannerieke J., Smit Egbert F., De Langen Adrianus J., Steeghs Neeltje, Beijnen Jos H., Huitema Alwin D.R. 1 Feb 2024, In: Therapeutic drug monitoring. 46 , p. 73-79 7 p.
van der Heijden L. T., Steeghs N., Beijnen J. H., Huitema A. D.R., Dorlo T. P.C. Dec 2023, In: Clinical and Translational Science. 16 , p. 2557-2564 8 p.
Lin Lishi, van der Meer Ellen K O, Steeghs Neeltje, Beijnen Jos H, Huitema Alwin D R 31 Oct 2023, In: Cancer Chemotherapy and Pharmacology. 93 , p. 129-136 8 p.
van der Kleij Maud B A, Guchelaar Niels A D, Mathijssen Ron H J, Versluis Jurjen, Huitema Alwin D R, Koolen Stijn L W, Steeghs Neeltje Oct 2023, In: Clinical Pharmacokinetics. 62 , p. 1333-1364 32 p.
Angus Lindsay, Smid Marcel, Wilting Saskia M, Bos Manouk K, Steeghs Neeltje, Konings Inge R H M, Tjan-Heijnen Vivianne C G, van Riel Johanna M G H, van de Wouw Agnes J, Cpct Consortium , Cuppen Edwin, Lolkema Martijn P, Jager Agnes, Sleijfer Stefan, Martens John W M 4 Sep 2023, In: Cancers. 15 14 p.
van Eerden Ruben A G, IJzerman Nikki S, van Meekeren Milan, Oomen-de Hoop Esther, Guchelaar Niels A D, Visser Andrea M W, Matic Maja, van Schaik Ron H N, de Bruijn Peter, Moes Dirk-Jan A R, Jobse Pieter A, Gelderblom Hans, Huitema Alwin D R, Steeghs Neeltje, Mathijssen Ron H J, Koolen Stijn L W, Aug 2023, In: Clinical Pharmacokinetics. 62 , p. 1129-1139 11 p.
Lanser Daan A C, Van der Kleij Maud B A, Veerman G D Marijn, Steeghs Neeltje, Huitema Alwin D R, Mathijssen Ron H J, Oomen-de Hoop Esther Jul 2023, In: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 163 6 p.
Groenland Stefanie L, Janssen J M, Nijenhuis C M, de Vries N, Rosing H, Wilgenhof S, van Thienen J V, Haanen J B A G, Blank C U, Beijnen J H, Huitema A D R, Steeghs N Jun 2023, In: Cancer Chemotherapy and Pharmacology. 91 , p. 447-456 10 p.
Mohmaed Ali Ma Ida, Bruin Maaike A C, Dezentjé Vincent O, Beijnen Jos H, Steeghs Neeltje, Huitema Alwin D R May 2023, In: Pharmaceutical Research. 40 , p. 1239-1247 9 p.