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dr. M.A.E. (Minke) Rab MSc

dr. M.A.E. (Minke) Rab MSc

Assistant Professor

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Research Output (20)

A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia

van Dijk Myrthe J., van Oirschot Brigitte A., Harrison Alexander N., Recktenwald Steffen M., Qiao Min, Stommen Amaury, Cloos Anne Sophie, Vanderroost Juliette, Terrasi Romano, Dey Kuntal, Bos Jennifer, Rab Minke A.E., Bogdanova Anna, Minetti Giampaolo, Muccioli Giulio G., Tyteca Donatienne, Egée Stéphane, Kaestner Lars, Molday Robert S., van Beers Eduard J., van Wijk Richard Dec 2023, In: American Journal of Hematology. 98 , p. 1877-1887 11 p.

Oxygen gradient ektacytometry-derived biomarkers are associated with acute complications in sickle cell disease

Rab Minke A E, Kanne Celeste K, Boisson Camille, Bos Jennifer, van Oirschot Brigitte A, Houwing Maite, Renoux Céline, Bartels Marije, Rijneveld Anita W, Nur Erfan, Cnossen Marjon H, Joly Philippe, Nader Elie, Fort Romain, Connes Philippe, van Wijk Richard, Sheehan Vivien A, van Beers Eduard J 17 Nov 2023, In: Blood Advances. 8 , p. 276-286 11 p.

One-year safety and efficacy of mitapivat in sickle cell disease:follow-up results of a phase 2, open-label study

van Dijk Myrthe J, Rab Minke A E, van Oirschot Brigitte A, Bos Jennifer, Derichs Cleo, Rijneveld Anita W, Cnossen Marjon H, Nur Erfan, Biemond Bart J, Bartels Marije, Jans Judith J M, van Solinge W W, Schutgens Roger E G, van Wijk Richard, van Beers Eduard J 7 Nov 2023, In: Blood Advances. 7 , p. 7539-7550 12 p.

Activation of pyruvate kinase as therapeutic option for rare hemolytic anemias:Shedding new light on an old enzyme

van Dijk Myrthe J, de Wilde Jonathan R A, Bartels Marije, Kuo Kevin H M, Glenthøj Andreas, Rab Minke A E, van Beers Eduard J, van Wijk Richard 12 Jun 2023, In: Blood Reviews. 61

Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease:a phase 2, open-label study

van Dijk Myrthe J, Rab Minke A E, van Oirschot Brigitte A, Bos Jennifer, Derichs Cleo, Rijneveld Anita W, Cnossen Marjon H, Nur Erfan, Biemond Bart J, Bartels Marije, Jans Judith J M, van Solinge Wouter W, Schutgens Roger E G, van Wijk Richard, van Beers Eduard J 5 Apr 2022, In: American Journal of Hematology. 97 , p. E226-E229

Comment on:Oxygen gradient ektacytometry does not predict pain in children with sickle cell anaemia

Sheehan Vivien A., van Beers Eduard J., Connes Philippe, van Wijk Richard, Rab Minke A.E. 2022, In: British Journal of Haematology. 197 , p. e61-e62

Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease

Boisson Camille, Rab Minke A E, Nader Elie, Renoux Céline, Kanne Celeste, Bos Jennifer, van Oirschot Brigitte A, Joly Philippe, Fort Romain, Gauthier Alexandra, Stauffer Emeric, Poutrel Solene, Kebaili Kamila, Cannas Giovanna, Garnier Nathalie, Renard Cécile, Hequet Olivier, Hot Arnaud, Bertrand Yves, van Wijk Richard, Sheehan Vivien A, van Beers Eduard J, Connes Philippe 5 Apr 2021, In: Cells. 10 , p. 1-11

Ektacytometry Analysis of Post-splenectomy Red Blood Cell Properties Identifies Cell Membrane Stability Test as a Novel Biomarker of Membrane Health in Hereditary Spherocytosis

Berrevoets M C, Bos J, Huisjes R, Merkx T H, van Oirschot B A, van Solinge W W, Verweij J W, Lindeboom M Y A, van Beers E J, Bartels M, van Wijk R, Rab M A E 25 Mar 2021, In: Frontiers in Physiology. 12 , p. 1-10

Decreased activity and stability of pyruvate kinase in sickle cell disease:a novel target for mitapivat therapy

Rab Minke A E, Bos Jennifer, van Oirschot Brigitte, Straaten Stephanie van, Kosinski Penelope A, Chubukov Victor, Kim Hyeryun, Mangus Heidi, Schutgens Roger E G, Pasterkamp Gerard, Dang Lenny, Kung Charles, van Beers Eduard J, van Wijk Richard 10 Mar 2021, In: Blood. 137 , p. 2997-3001 5 p.

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