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prof. dr. S.M.A. Lens Full Professor

  • Group Lens, section Molecular Cancer Research

Contact

Research Programs

Side Activities

  • Organizer of the EMBO Workshop on Chromosome Segregation and Aneuploidy (2013)

    Member of the NWO Rubicon evaluation committee (2015)

    Member of the NWO-ALW Open Program evaluation committee (2016)

    ERC Advanced Grant Evaluation panel member (2017/2018)

    Member evaluation committee of the Max Puritz Labs, Univ. of Vienna, Austria (2019)

    Member of organizing committee of Life2020 (NWO)

    PI of Oncode Institute

Research Output (70)

Human chromosome-specific aneuploidy is influenced by DNA-dependent centromeric features

Dumont Marie, Gamba Riccardo, Gestraud Pierre, Klaasen Sjoerd, Worrall Joseph T., De Vries Sippe G., Boudreau Vincent, Salinas-Luypaert Catalina, Maddox Paul S., Lens Susanne M.A., Kops Geert J.P.L., McClelland Sarah E., Miga Karen H., Fachinetti Daniele 15 jan 2020, In: EMBO Journal. 39 21 p.

PLK1 plays dual roles in centralspindlin regulation during cytokinesis

Adriaans Ingrid E, Basant Angika, Ponsioen Bas, Glotzer Michael, Lens Susanne M A 1 apr 2019, In: Journal of Cell Biology. 218 , p. 1250-1264 15 p.

Cytokinesis defects and cancer

Lens Susanne M.A., Medema René H. 1 jan 2018, In: Nature Reviews Cancer. 19 , p. 32-45 14 p.

Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics

DeLuca Keith F., Meppelink Amanda, Broad Amanda J., Mick Jeanne E., Peersen Olve B., Pektas Sibel, Lens Susanne M.A., DeLuca Jennifer G. 1 jan 2018, In: Journal of Cell Biology. 217 , p. 163-177 15 p.

The ins and outs of Aurora B inner centromere localization

Hindriksen Sanne, Lens Susanne M.A., Hadders Michael A. 22 dec 2017, In: Frontiers in Cell and Developmental Biology. 5

Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing

Hengeveld Rutger C C, Vromans Martijn J M, Vleugel Mathijs, Hadders Michael A, Lens Susanne M A 2017, In: Nature Communications [E]. 8

Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells

Hindriksen Sanne, Bramer Arne J, Truong My Anh, Vromans Martijn J M, Post Jasmin B, Verlaan-Klink Ingrid, Snippert Hugo J , Lens Susanne M A, Hadders Michael A 2017, In: PLoS ONE [E]. 12

Tetraploid/Diploid Mosaicism in Cultured Genital Skin Fibroblasts:Is It Causally Related to Penoscrotal Hypospadias

Giltay Jacques C., Klijn Aart J., de Jong Tom P V M, Kats Peter, van Breugel Marjolein, Lens Susan, Vromans Martijn, Van Der Veken Lars T., Hochstenbach Ron 1 jul 2016, In: Molecular Syndromology. 7 , p. 153-159 7 p.

Chromosome segregation regulation in human zygotes:Altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex

Van De Werken C., Avo Santos M., Laven J. S E, Eleveld C., Fauser B. C J M, Lens S. M A, Baart E. B. 1 okt 2015, In: Human Reproduction. 30 , p. 2275-2291 17 p.

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability

Hengeveld Rutger C C, Schoonen Pepijn M, de Vries Elisabeth G E, Lens Susanne M A, van Vugt Marcel A T M 24 aug 2015, In: Developmental Cell. 34 , p. 466-474 9 p.

All Research Output (70)
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